Programming of the brain

During the early-life period, our brain develops at an amazing rate. When this period is disturbed by exposure childhood adversity, it can have a lasting impact on the adult we become. Indeed, exposure to early-life stress is associated with impaired learning and memory and a higher risk for psychopathology in later life. Because prevention of early-life stress is often difficult, a better understanding of the mechanisms that underlie the early programming of the brain and behavior is needed.

 

The main goal of our research group is to better understand the biological mechanisms and environmental factors involved in brain programming by stressful early-life experiences and to test the efficacy of (nutritional) interventions. 

The interplay of early-life stress, nutrition, and immune activation programs adult hippocampal structure and function 
doi: 10.3389/fnmol.2014.00103
Chronic early life stress alters developmental and adult neurogenesis and impairs cognitive function in mice
doi: 10.1002/hipo.22374

FEATURED PUBLICATIONS

Perinatal programming of hippocampal structure and function; emerging roles of stress, neurogenesis, epigenetics and early nutrition
doi: 10.1016/j.tins.2013.08.002

THE KOROSI-LAB

Our research in the news.

Our research team, headed by Aniko Korosi, consists of 5 PhD-students and 3 post-docs