Programming of the brain
During the early-life period, our brain develops at an amazing rate. When this period is disturbed by exposure childhood adversity, it can have a lasting impact on the adult we become. Indeed, exposure to early-life stress is associated with impaired learning and memory and a higher risk for psychopathology in later life. Because prevention of early-life stress is often difficult, a better understanding of the mechanisms that underlie the early programming of the brain and behavior is needed.
The main goal of our research group is to better understand the biological mechanisms and environmental factors involved in brain programming by stressful early-life experiences and to test the efficacy of (nutritional) interventions.
FEATURED PUBLICATIONS
Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions
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doi: 10.1038/s41398-022-02265-6.
Early-life stress and dietary fatty acids impact the brain lipid/oxylipin profile into adulthood, basally and in response to LPS
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doi: 10.3389/fimmu.2022.967437
Comparing the human milk antibody response after vaccination with four COVID-19 vaccines: A prospective, longitudinal cohort study in the Netherlands
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doi: 10.1016/j.eclinm.2022.101393
THE KOROSI-LAB
Our research in the news.
Our research team, headed by Aniko Korosi.